154: a Pharmacoeconomic Evaluation to Make Decision: Is the Use of Simvastatin 10 mg as an Otc Medication Cost-effective for the Primary Prevention of Stroke amongst Women in Iran?
نویسندگان
چکیده
Background and aims: Cardiovascular disease (CVD) is one of the most important causes of death and disability in Iran. Stroke is a serious cardiovascular situation which poses many problems for both patients and societies. Considering the pleiotropic effects of statins and their safety, particularly in low doses, as well as the increasing trend of stroke in Iranian populations, the economic evaluation techniques were used in this study to support decision-making regarding the use of simvastatin 10mg as an OTC drug for the primary prevention of stroke among women with an average CVD risk in Iran. Methods: A semi-Markov model was developed in this study to investigate both cost-utility (using QALY or Quality-Adjusted-
منابع مشابه
The Economic Burden of Stroke Based on South Korea’s National Health Insurance Claims Database
Background This study was conducted to determine the scale and the nature of the economic burden caused by strokes and to use the results as an evidential source for determining the allocation of South Korea stroke cases in 2015. Methods For research subjects, the study analyzed demographic characteristics and economic burden based on data from national health insurance (NHI) claims for inpat...
متن کاملEvaluation of cytotoxic and apoptotic effects of simvastatin in Bone Cancer Cell line (MG-63)
Background & aim: Cancer is a disharmony amongst cell growth and death which results in accumulation of cells. Bone cancer is an absolutely dangerous type of cancer and occurs when the bone-making cells are disrupted. Despite some reports on the anticancer effects of simvastatin, the activity of simvastatin on bone cancer cells has not been reported. The aim of this study was to evaluate the cy...
متن کاملThe effect of simvastatin in prevention of histological changes of substantia nigra and behavioral abnormalities in an experimental model of Parkinson’s disease in rat
Background and Objective: Parkinson’s disease (PD) is a rather common neurological disorder in elders that is due to degeneration of dopaminergic neurons within mesencephalic substantia nigra pars compacta. With regard to protective and antioxidant effect of simvastatin, this study was conducted to evaluate its neuroprotective effect in an experimental model of PD. Materials and Methods: In thi...
متن کاملEconomic Analysis of Bisphosphonate Use after Distal Radius Fracture for Prevention of Hip Fracture
Background: Osteoporosis is a common condition among the elderly population, and is associated with an increased risk of fracture. One of the most common fragility fractures involve the distal radius, and are associated with risk of subsequent fragility fracture. Early treatment with bisphosphonates has been suggested to decrease the population hip fracture burden. However, there have been no p...
متن کاملEconomic Evaluation of Infliximab for Treatment of Refractory Ulcerative Colitis in Iran: Cost-Effectiveness Analysis
The aim of this study is to assess cost-effectiveness of infliximab, compared with conventional treatments in patients with moderate to severe Ulcerative Colitis (UC) in Iran. We developed an analytical decision model with a 5-year-time horizon to follow up 1000 hypothetical patients, in order to estimate treatment costs and outcomes. Hypothetical patients, were individuals with moderate to sev...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 7 شماره
صفحات -
تاریخ انتشار 2017